Toward understanding non-coding RNA roles in intracranial aneurysms and subarachnoid hemorrhage

Toward understanding non-coding RNA roles in intracranial aneurysms and subarachnoid hemorrhage

Blog Article

Subarachnoid hemorrhage (SAH) is a common and frequently life-threatening cerebrovascular disease, which is mostly related with a ruptured intracranial aneurysm.Its complications include rebleeding, early brain injury, cerebral vasospasm, delayed cerebral ischemia, chronic hydrocephalus, and also non neurological problems.Non-coding RNAs (ncRNAs), comprising of Sharpening Stone microRNAs (miRNAs), small interfering RNAs (siRNAs) and long non-coding RNAs (lncRNAs), play an important role in intracranial aneurysms and SAH.

Here, we review the non-coding RNAs expression profile and their related mechanisms in intracranial aneurysms and SAH.Moreover, we suggest that these non-coding RNAs function as novel molecular biomarkers Measurement Kits to predict intracranial aneurysms and SAH, and may yield new therapies after SAH in the future.